BDBM472289 2-cyclopropyl-1-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)methyl)-N-(4-::US10829481, Compound I-105

SMILES CCS(=O)(=O)c1ccc(CNC(=O)c2ccc3n(Cc4ccc5OC(F)(F)Oc5c4)c(nc3c2)C2CC2)cc1

InChI Key InChIKey=MAYFKUUMLYRJJL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472289   

TargetNuclear receptor ROR-gamma(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 472289BDBM472289(2-cyclopropyl-1-((2,2-difluorobenzo[d][1,3]dioxol-...)
Affinity DataKi:  550nMAssay Description:Compounds described herein were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-ligand (RL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
US Patent