BDBM474354 (S)-6-((S)-(3-fluorophenyl)(4- fluorophenyl)methyl)-11-hydroxy-5,6-dihydro- 10H-imidazo[2',1':3,4]pyrazino[1,2- b]pyridazin-10-one::US10858366, Example 24::US11453677, Example 24

SMILES Oc1c2-c3nccn3C[C@H]([C@@H](c3ccc(F)cc3)c3cccc(F)c3)n2ncc1=O

InChI Key InChIKey=RRSGFQKVFSAQGW-MJGOQNOKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474354   

TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474354((S)-6-((S)-(3-fluorophenyl)(4- fluorophenyl)methyl...)
Affinity DataIC50:  9nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474354((S)-6-((S)-(3-fluorophenyl)(4- fluorophenyl)methyl...)
Affinity DataIC50:  9nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent