BDBM474363 (S)-6-benzhydryl-11-hydroxy-3- (methoxymethyl)-5,6-dihydro-10H- imidazo[1,2-a]pyrido[2,1-c]pyrazin-10-one::US10858366, Example 56::US11453677, Example 56

SMILES COCc1cnc2-c3c(O)c(=O)ccn3[C@H](Cn12)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=NQNDVFYVYOLQPV-HXUWFJFHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474363   

TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474363((S)-6-benzhydryl-11-hydroxy-3- (methoxymethyl)-5,6...)
Affinity DataIC50:  100nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolymerase acidic protein()
Novartis

US Patent
LigandPNGBDBM474363((S)-6-benzhydryl-11-hydroxy-3- (methoxymethyl)-5,6...)
Affinity DataIC50:  100nMAssay Description:Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent