BDBM475400 1-{5-[3-(3-Chloro-benzyloxy)-phenyl]-1H-benzoimidazol-::US10851083, Example 12::US11618744, Example 12

SMILES OC(=O)c1cnn(c1)-c1nc2cc(ccc2[nH]1)-c1cccc(OCc2cccc(Cl)c2)c1

InChI Key InChIKey=SAHAFELAYUNCQY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475400   

TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475400(1-{5-[3-(3-Chloro-benzyloxy)-phenyl]-1H-benzoimida...)
Affinity DataIC50:  31.6nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475400(1-{5-[3-(3-Chloro-benzyloxy)-phenyl]-1H-benzoimida...)
Affinity DataIC50:  31.6nMAssay Description:The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent