BDBM475451 1-[6-Chloro-5-(3,4-dichloro-phenylsulfanyl)-1H-::US10851083, Example 63::US11618744, Example 63

SMILES O=C(O)c1cnn(-c2nc3cc(Sc4ccc(Cl)c(Cl)c4)c(Cl)cc3[nH]2)c1

InChI Key InChIKey=DGVSUCGZFPIXOP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475451   

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475451BDBM475451(1-[6-Chloro-5-(3,4-dichloro-phenylsulfanyl)-1H- | ...)
Affinity DataIC50: 661nMAssay Description:The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475451BDBM475451(1-[6-Chloro-5-(3,4-dichloro-phenylsulfanyl)-1H- | ...)
Affinity DataIC50: 661nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent