BDBM475500 1-(4,6-Difluoro-1H-benzoimidazol-2-yl)-1H-pyrazole-4-::US10851083, Example 112::US11618744, Example 112

SMILES OC(=O)c1cnn(c1)-c1nc2c(F)cc(F)cc2[nH]1

InChI Key InChIKey=JWAJEIQASIWFMK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475500   

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475500BDBM475500(1-(4,6-Difluoro-1H-benzoimidazol-2-yl)-1H-pyrazole...)
Affinity DataIC50: 158nMAssay Description:The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2021
Entry Details
US Patent

TargetEgl nine homolog 1 [181-417](Human)
Janssen Pharmaceutica

US Patent
LigandChemical structure of BindingDB Monomer ID 475500BDBM475500(1-(4,6-Difluoro-1H-benzoimidazol-2-yl)-1H-pyrazole...)
Affinity DataIC50: 158nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2023
Entry Details
US Patent