BDBM475557 1-[6-Chloro-5-(4-methyl-benzylsulfanyl)-1H-::US10851083, Example 169::US10851083, Example 178::US11618744, Example 178

SMILES Cc1ccc(CS(=O)(=O)c2cc3nc([nH]c3cc2Cl)-n2cc(cn2)C(O)=O)cc1

InChI Key InChIKey=TUNFONZLEMUBTD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 475557   

TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475557(1-[6-Chloro-5-(4-methyl-benzylsulfanyl)-1H- | US10...)
Affinity DataIC50:  200nMAssay Description:The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475557(1-[6-Chloro-5-(4-methyl-benzylsulfanyl)-1H- | US10...)
Affinity DataIC50:  20nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475557(1-[6-Chloro-5-(4-methyl-benzylsulfanyl)-1H- | US10...)
Affinity DataIC50:  20nMAssay Description:The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent