BDBM475558 1-[6-Chloro-5-(4-trifluoromethyl-benzylsulfanyl)-1H-::US10851083, Example 170::US11618744, Example 170

SMILES OC(=O)c1cnn(c1)-c1nc2cc(SCc3ccc(cc3)C(F)(F)F)c(Cl)cc2[nH]1

InChI Key InChIKey=JYOCLJOXUYCWKD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475558   

TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475558(1-[6-Chloro-5-(4-trifluoromethyl-benzylsulfanyl)-1...)
Affinity DataIC50:  200nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475558(1-[6-Chloro-5-(4-trifluoromethyl-benzylsulfanyl)-1...)
Affinity DataIC50:  200nMAssay Description:The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent