BDBM476368 US10875851, Example 24::naphthalen-1-yl (3S)-3-{[4- (aminomethyl)-3- methoxybenzyl]carbamoyl}-4-(N,3- dicyclohexyl-D-alanyl)piperazine-1- carboxylate

SMILES COc1cc(CNC(=O)[C@@H]2CN(CCN2C(=O)[C@@H](CC2CCCCC2)NC2CCCCC2)C(=O)Oc2cccc3ccccc23)ccc1CN

InChI Key InChIKey=BUVDEKOTUUFCCI-GPOMZPHUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476368   

TargetCoagulation factor XII(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476368(US10875851, Example 24 | naphthalen-1-yl (3S)-3-{[...)
Affinity DataIC50:  1.60nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIIa can be determined using a relevant purified serin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent