BDBM476482 (2S)-4[(4S,5S)-5-(3-cyanophenyl)-4- methyl-4,5-dihydro-1,3-oxazol-2-yl]- 1-(N2-cyclohexyl-N6,N6-dimethyl-D- lysyl)-N-(thiophen-2- ylmethyl)piperazine-2-carboxamide::US10875851, Example 138

SMILES C[C@@H]1N=C(O[C@H]1c1cccc(c1)C#N)N1CCN([C@@H](C1)C(=O)NCc1cccs1)C(=O)[C@@H](CCCCN(C)C)NC1CCCCC1

InChI Key InChIKey=FKXSEWPZWBQOMC-QGWJVEIISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476482   

TargetCoagulation factor XII(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476482((2S)-4[(4S,5S)-5-(3-cyanophenyl)-4- methyl-4,5-dih...)
Affinity DataIC50:  1.40nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIIa can be determined using a relevant purified serin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent