BDBM476517 (2S)-1-[N-(1-methylethyl)-6-piperidin- 1-yl-D-norleucyl]-4-[(4S,5S)-4- methyl-5-phenyl-4,5-dihydro-1,3- oxazol-2-yl]-N-(thieno[3,2-c]pyridin- 2-ylmethyl)piperazine-2-carboxamide::US10875851, Example 173

SMILES CC(C)N[C@H](CCCCN1CCCCC1)C(=O)N1CCN(C[C@H]1C(=O)NCc1cc2cnccc2s1)C1=N[C@@H](C)[C@@H](O1)c1ccccc1

InChI Key InChIKey=BZLJCIDLKRVGKU-KZJZXYEKSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476517   

TargetCoagulation factor XII(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476517((2S)-1-[N-(1-methylethyl)-6-piperidin- 1-yl-D-norl...)
Affinity DataIC50:  3.90nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIIa can be determined using a relevant purified serin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent