BDBM477050 US10882857, Example 1.02::US11673888, Example 1.02

SMILES O=C(N1Cc2ccc(cc2C1)C(=O)N1CCc2[nH]nnc2C1)c1cnc(OCC2CCOCC2)c(c1)C1CC1

InChI Key InChIKey=CFAQZQWHUIGDQS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 477050   

TargetAtaxin-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM477050(US10882857, Example 1.02 | US11673888, Example 1.0...)
Affinity DataIC50:  8nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM477050(US10882857, Example 1.02 | US11673888, Example 1.0...)
Affinity DataIC50:  8nMAssay Description:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;ATX solution: ATX (human His-tagged) stock so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent