BDBM477604 (R)—N-(1-(2-methylphenyl)-4,5,6,7-tetrahydro-1H-indazol-4-34)-4,5,6,7-tetrahydrobenzo[d]isoxazole-3-carboxamide::US10889564, Example 34
SMILES Cc1ccccc1-n1ncc2[C@@H](CCCc12)NC(=O)c1noc2CCCCc12
InChI Key InChIKey=HUVJSRAMULDASL-QGZVFWFLSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 477604
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 3nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human DHODH using dihydroorotic acid as substrate in presence of 2 nM of DHODH by DCIP assayMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human DHODH using dihydroorotic acid as substrate measured for 68 mins by DCIP based colorimetric assayMore data for this Ligand-Target Pair