BDBM477645 6-Fluoro-1-(1-(4-(6-methoxypyridin-3-yl)-5-methyl-4H-1,2,4-triazol-3-yl)azetidin-3-yl)-1,2,3,4-tetrahydroquinoline 29::US10889569, Example 29

SMILES COc1ccc(cn1)-n1c(C)nnc1N1CC(C1)N1CCCc2cc(F)ccc12

InChI Key InChIKey=WIGLBHPFUXYPEA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 477645   

TargetVasopressin V1a receptor(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM477645(6-Fluoro-1-(1-(4-(6-methoxypyridin-3-yl)-5-methyl-...)
Affinity DataIC50:  6.20E+3nMAssay Description:V1aR: The inhibition effect of the compounds of the present invention on the activity of human V1 aR protein expressed in HEK293/human V1aR stably tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVasopressin V2 receptor(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM477645(6-Fluoro-1-(1-(4-(6-methoxypyridin-3-yl)-5-methyl-...)
Affinity DataIC50:  1.21E+4nMAssay Description:V2R: The inhibition effect of the compounds of the present invention on the activity of human V2R protein expressed in HEK293/human V2R cells was det...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVasopressin V1b receptor(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM477645(6-Fluoro-1-(1-(4-(6-methoxypyridin-3-yl)-5-methyl-...)
Affinity DataIC50:  9.51E+4nMAssay Description:V1bR: The inhibition effect of the compounds of the present invention on the activity of human V1bR protein expressed in HEK293/human V1bR cells was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent