BDBM477660 5-Fluoro-1-(1-(5-(methoxymethyl)-4-(6-methoxypyridin-3-yl)-4H-1,2,4-triazol-3-yl) azetidin-3-yl)indoline 23::US10889569, Example 23

SMILES COCc1nnc(N2CC(C2)N2CCc3cc(F)ccc23)n1-c1ccc(OC)nc1

InChI Key InChIKey=CYFKNIQLHUBQCE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 477660   

TargetVasopressin V2 receptor(Human)
Jiangsu Hengrui Medicine

US Patent
LigandChemical structure of BindingDB Monomer ID 477660BDBM477660(US10889569, Example 23 | 5-Fluoro-1-(1-(5-(methoxy...)
Affinity DataIC50: 5.20E+4nMAssay Description:V2R: The inhibition effect of the compounds of the present invention on the activity of human V2R protein expressed in HEK293/human V2R cells was det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
US Patent