BDBM478092 1-((3-(3-chloro-5-cyanoindolizin-8-yl)pyridin- 4-yl)thio)cyclobutane-1-carboxylic acid::US10894038, Example 10::US10894038, Example 24

SMILES OC(=O)C1(CCC1)Sc1ccncc1-c1ccc(C#N)n2c(Cl)ccc12

InChI Key InChIKey=MCIZYYHYXDNXRH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 478092   

TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM478092(1-((3-(3-chloro-5-cyanoindolizin-8-yl)pyridin- 4-y...)
Affinity DataIC50:  34nMAssay Description:HEK293-URAT1 cell Lines were donated by Japan Fuji Biomedical Research Institute. Negative control cell of HEK293 (MOCK cells) which was transfected ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM478092(1-((3-(3-chloro-5-cyanoindolizin-8-yl)pyridin- 4-y...)
Affinity DataIC50:  424nMAssay Description:HEK293-URAT1 cell Lines were donated by Japan Fuji Biomedical Research Institute. Negative control cell of HEK293 (MOCK cells) which was transfected ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent