BDBM478782 (Isomer-1 of compound-35): 2-(1''-acryloyl-1'',2'',5'',6''-tetrahydro-[2,3''-bipyridin]- 5-yl)-N-(5-cyclopropyl-1H-pyrazol-3-yl)propanamide::US10894786, Comp. No 36::US10894786, Comp. No 37
SMILES CC(C(=O)Nc1cc([nH]n1)C1CC1)c1ccc(nc1)C1=CCCN(C1)C(=O)C=C
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 478782
Affinity DataKd: 63nMAssay Description:Kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli were grown to log-ph...More data for this Ligand-Target Pair
Affinity DataIC50: 686nMAssay Description:The inhibitory activity of the test compounds was assessed by the LANCE TR-FRET assay, which detects the ATP-dependent phosphorylation of an ULight-4...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:The inhibitory activity of the test compounds was assessed by the LANCE TR-FRET assay, which detects the ATP-dependent phosphorylation of an ULight-4...More data for this Ligand-Target Pair
Affinity DataIC50: 153nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair