BDBM479328 (3-((3S,4S)-4-amino-3-methyl-2-oxa-8- azaspiro[4.5]decan-8-yl)-6-(((S)-6a',7'-dihydro- 6'H,9'H-spiro[cyclopropan-1,8'-pyrido[3,2- b]pyrrolo[1,2-d][1,4]oxazin]-4'-yl)thio)pyrazin- 2-yl)methanol::US10894797, Compound 17::US11459340, Compound 20::US11518772, Compound 17
SMILES C[C@@H]1OCC2(CCN(CC2)c2ncc(Sc3ccnc4N5CC6(CC6)CC5COc34)nc2CO)[C@@H]1N
InChI Key InChIKey=BYYBBLNEXZRDQB-LWCIBLMUSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 479328
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Nikang Therapeutics
US Patent
Nikang Therapeutics
US Patent
Affinity DataIC50: 2nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Nikang Therapeutics
US Patent
Nikang Therapeutics
US Patent
Affinity DataIC50: 2nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:The phosphatase reactions were carried out at room temperature in 384-well black polystyrene plates (Greiner Bio-One, Cat #784076) using assay buffer...More data for this Ligand-Target Pair