BDBM479518 3-amino-N-((6-amino-3-fluoropyridin- 2-yl)methyl)-6-(1-methyl-6-oxo-1,6-di- hydropyridin-3-yl)-5-(oxazol-2-yl) pyrazine-2-carboxamide::US10898481, Compound 49::US11571420, Compound 49

SMILES Cn1cc(ccc1=O)-c1nc(C(=O)NCc2nc(N)ccc2F)c(N)nc1-c1ncco1

InChI Key InChIKey=CBXYJZBCLYHQEG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 479518   

TargetAdenosine receptor A2a(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM479518(3-amino-N-((6-amino-3-fluoropyridin- 2-yl)methyl)-...)
Affinity DataIC50:  5.30nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM479518(3-amino-N-((6-amino-3-fluoropyridin- 2-yl)methyl)-...)
Affinity DataIC50:  117nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM479518(3-amino-N-((6-amino-3-fluoropyridin- 2-yl)methyl)-...)
Affinity DataIC50:  5.30nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM479518(3-amino-N-((6-amino-3-fluoropyridin- 2-yl)methyl)-...)
Affinity DataIC50:  117nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent