BDBM480432 3-(tert-butyl)-N-(4-(4-((1-methyl-1H-pyrazol-3-yl)amino)-1,3,5-triazin-2-yl)-2-(trifluoromethyl)benzyl)-1,2,4-oxadiazole-5-carboxamide ::US10899753, Example 8

SMILES Cn1ccc(Nc2ncnc(n2)-c2ccc(CNC(=O)c3nc(no3)C(C)(C)C)c(c2)C(F)(F)F)n1

InChI Key InChIKey=HSSBPEZKXQMAMK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480432   

TargetTyrosine-protein kinase BTK(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 480432BDBM480432(3-(tert-butyl)-N-(4-(4-((1-methyl-1H-pyrazol-3-yl)...)
Affinity DataIC50: 5.5nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2021
Entry Details
US Patent