BDBM481806 (R)-3-((6-chloro-2,3- dihydro-1H-inden-1- yl)methyl)-5-((7-methyl-6- oxo-6,7-dihydro-1H-purin- 1-yl)methyl-1,3,4-oxadiazol- 2(3H)-one::US10913742, Example 48

SMILES Cn1cnc2ncn(Cc3nn(C[C@@H]4CCc5ccc(Cl)cc45)c(=O)o3)c(=O)c12

InChI Key InChIKey=JYTFGJCBRILOIU-LBPRGKRZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481806   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM481806((R)-3-((6-chloro-2,3- dihydro-1H-inden-1- yl)methy...)
Affinity DataIC50:  196nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent