BDBM481847 5-[[4-[3-(4- chlorophenyl)cyclobutyl]-5- oxo-1,3,4-oxadiazol-2- yl]methyl]-3-methyl- isoxazolo[5,4-d]pyrimidin- 4-one::US10913742, Example 91
SMILES Cc1noc2ncn(Cc3nn([C@H]4C[C@@H](C4)c4ccc(Cl)cc4)c(=O)o3)c(=O)c12
InChI Key InChIKey=ANROYDNBUBEGHC-MQMHXKEQSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 481847
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 36.2nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair