BDBM482229 Cyclohexanesulfonic acid [3-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-fluoro-phenyl]-amide ::US10918642, Cmpd # 89::US11491158, Cmpd 89
SMILES Cn1cc(-c2cccc(NS(=O)(=O)C3CCCCC3)c2F)c2c(N)ncnc12
InChI Key InChIKey=TUYXBQNRMZCKPH-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 482229
TargetEukaryotic translation initiation factor 2-alpha kinase 3 [540-1115](Homo sapiens (Human))
Nerviano Medical Sciences
US Patent
Nerviano Medical Sciences
US Patent
Affinity DataIC50: >160nMAssay Description:The biochemical activity of compounds was determined by incubation with PERK recombinant enzyme (cytoplasmic domain corresponding to residues 540-111...More data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Nerviano Medical Sciences
US Patent
Nerviano Medical Sciences
US Patent
Affinity DataIC50: >160nMAssay Description:Serially diluted compounds were incubated for 60 minutes at room temperature in the presence of ATP/P33 gammaATP mix, substrate and enzyme in a volum...More data for this Ligand-Target Pair