BDBM483758 (R)-1-(4-((3-fluoro- [1,1'-biphenyl]-4- yl)methyl)-2- methylpiperazine-1- carbonyl)-1H- pyrazole-3- carboxylic acid::US10927105, Ex 253::US11655217, Example 253

SMILES C[C@@H]1CN(Cc2ccc(cc2F)-c2ccccc2)CCN1C(=O)n1ccc(n1)C(O)=O

InChI Key InChIKey=AMDQMEIEJVPVKP-MRXNPFEDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483758   

TargetMonoglyceride lipase(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM483758((R)-1-(4-((3-fluoro- [1,1'-biphenyl]-4- yl)methyl)...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM483758((R)-1-(4-((3-fluoro- [1,1'-biphenyl]-4- yl)methyl)...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent