BDBM483836 4-chloro-1-(4-(4- (pyrrolidin-1-yl)-2- (trifluoromethyl)- benzyl)piperazine-1- carbonyl)-1H- pyrazole-3- carboxylic acid::US10927105, Ex 368::US11655217, Example 368

SMILES OC(=O)c1nn(cc1Cl)C(=O)N1CCN(Cc2ccc(cc2C(F)(F)F)N2CCCC2)CC1

InChI Key InChIKey=QVKHIWLYPWMFON-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 483836   

TargetMonoglyceride lipase(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM483836(4-chloro-1-(4-(4- (pyrrolidin-1-yl)-2- (trifluorom...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM483836(4-chloro-1-(4-(4- (pyrrolidin-1-yl)-2- (trifluorom...)
Affinity DataIC50: <100nMAssay Description:Proteomes (mouse brain membrane fraction for mouse assays; human prefrontal cortex membrane fractions for human assays) (50 mL, 1.0 mg/mL total prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent