BDBM484307 (R)-1-(3-(8-ethyl-1-(4-(2-fluoro-3- methoxyphenoxy)phenyl)imidazo[1,5- a]pyrazin-3-yl)pyrrolidin-1-yl)prop-2- en-1-one::US10933063, Compound 106::US11554118, Compound 106

SMILES CCc1nccn2c(nc(-c3ccc(Oc4cccc(OC)c4F)cc3)c12)[C@@H]1CCN(C1)C(=O)C=C

InChI Key InChIKey=VJFYKBMXKUSEHO-LJQANCHMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 484307   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Suzhou Baijibugong Pharmaceutical Technology

US Patent
LigandPNGBDBM484307((R)-1-(3-(8-ethyl-1-(4-(2-fluoro-3- methoxyphenoxy...)
Affinity DataIC50: <10nMAssay Description:Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were performed in a reaction volume...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticleUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Suzhou Baijibugong Pharmaceutical Technology

US Patent
LigandPNGBDBM484307((R)-1-(3-(8-ethyl-1-(4-(2-fluoro-3- methoxyphenoxy...)
Affinity DataIC50:  30nMAssay Description:Btk and Other Kinases: Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were perform...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent