BDBM485739 3-(isoquinolin-5-yloxy)-N- methyl-3-(6- (trifluoromethyl)pyridin-2- yl)propan-1-amine::US10941138, Example 37

SMILES CNCCC(Oc1cccc2cnccc12)c1cccc(n1)C(F)(F)F

InChI Key InChIKey=ABWJALRTUMQAIS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 485739   

TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Esteve Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 485739BDBM485739(3-(isoquinolin-5-yloxy)-N- methyl-3-(6- (trifluoro...)
Affinity DataKi: >3.00E+3nMAssay Description:Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
US Patent