BDBM486399 N-(1,1-dioxidotetrahydrothiophen- 3-yl)-1-(4-fluorophenyl)-3-[3- (trifluoromethyl)phenyl]-1H- indole-6-carboxamide (racemic)::US10947222, Example 30

SMILES Fc1ccc(cc1)-n1cc(-c2cccc(c2)C(F)(F)F)c2ccc(cc12)C(=O)NC1CCS(=O)(=O)C1

InChI Key InChIKey=OIZBROMVFORZNF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 486399   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM486399(N-(1,1-dioxidotetrahydrothiophen- 3-yl)-1-(4-fluor...)
Affinity DataIC50:  18nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent