BDBM50007200 CHEMBL3237873

SMILES [H][C@@]12C[C@@]([H])(C1(C)C)[C@]1(C)OB(O[C@]1([H])C2)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)NCCCCOCc1ccccc1)NC(C)=O

InChI Key InChIKey=ODIWGDQSSAWSIL-GKWCIWIWSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50007200   

TargetProteasome subunit beta type-7(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50007200(CHEMBL3237873)
Affinity DataIC50:  170nMAssay Description:Inhibition of caspase-like activity of human 20S proteasome using Ac-nLPnLD-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50007200(CHEMBL3237873)
Affinity DataIC50:  280nMAssay Description:Inhibition of beta5 subunit of immunoproteasome (unknown origin) by active-site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-7(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50007200(CHEMBL3237873)
Affinity DataIC50:  2.17E+3nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome using Ac-RLR-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50007200(CHEMBL3237873)
Affinity DataIC50:  59nMAssay Description:Inhibition of beta5i subunit of immunoproteasome (unknown origin) by active-site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50007200(CHEMBL3237873)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant cathepsin B (unknown origin) using Z-Leu-Arg-AMC as substrate by spectrofluorometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50007200(CHEMBL3237873)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant cathepsin G (unknown origin) using Suc-Ala-Ala-Pro-Phe-AMC as substrate by spectrofluorometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-7(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50007200(CHEMBL3237873)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-LLVY-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal protective protein(Homo sapiens (Human))
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50007200(CHEMBL3237873)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of recombinant cathepsin A (unknown origin) using Mca-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys(Dnp)-OH as substrate incubated with enzyme for 5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed