BDBM50014351 CHEMBL323373::Sodium; 8-(2-tert-butyl-2H-tetrazol-5-yl)-9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-nona-6,8-dienoate

SMILES [#6]C([#6])([#6])n1nnc(n1)\[#6](\[#6]=[#6]\[#6@@H](-[#8])-[#6]-[#6@@H](-[#8])-[#6]-[#6](-[#8-])=O)=[#6](/c1ccc(F)cc1)-c1ccc(F)cc1

InChI Key InChIKey=VTYNAOFVUPXGON-DDVDASKDSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50014351   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014351(CHEMBL323373 | Sodium; 8-(2-tert-butyl-2H-tetrazol...)
Affinity DataIC50:  3.70E+3nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductase using [2-14C]-acetate incorporationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50014351(CHEMBL323373 | Sodium; 8-(2-tert-butyl-2H-tetrazol...)
Affinity DataIC50:  3.70E+3nMAssay Description:In vitro inhibitory activity was measured against rat liver HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed