BDBM50016461 (S)-2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-benzoylamino}-pentanedioic acid::CHEMBL293263::GNF-PF-173

SMILES Nc1nc(N)c2nc(CCc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cnc2n1

InChI Key InChIKey=LGFLRHWJJKLPCC-ZDUSSCGKSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50016461   

TargetDihydrofolate reductase(Lactobacillus casei)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016461((S)-2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-ben...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016461((S)-2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-ben...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016461((S)-2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-ben...)
Affinity DataIC50:  21nMAssay Description:Inhibitory activity against dihydrofolate reductase in Lactobacillus casei was determined (glutamate residue 5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016461((S)-2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-ben...)
Affinity DataIC50:  18nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016461((S)-2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-ben...)
Affinity DataIC50:  34nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
University Of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016461((S)-2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-ben...)
Affinity DataIC50:  22nMAssay Description:Inhibitory activity of the compound against dihydrofolate reductase in Lactobacillus casei was determined (glutamate resedue 6)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed