BDBM50023331 (+)-pyrido[3,4-b]homotropane::(+/-)-pyrido[3,4-b]homotropane::(-)-pyrido[3,4-b]homotropane::4,13-Diaza-tricyclo[8.2.1.0*2,7*]trideca-2(7),3,5-triene::4,13-Diaza-tricyclo[8.2.1.0*2,7*]trideca-2(7),3,5-triene(PHT)::CHEMBL149667

SMILES C1CC2NC1CCc1ccncc21

InChI Key InChIKey=TXCZFZKWSPPSHR-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50023331   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50023331((+)-pyrido[3,4-b]homotropane | (+/-)-pyrido[3,4-b]...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity for nicotinic acetylcholine receptor alpha 7 from human neuroblastoma SH-SY5Y cells; n=3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Stauffer Chemical

Curated by ChEMBL
LigandPNGBDBM50023331((+)-pyrido[3,4-b]homotropane | (+/-)-pyrido[3,4-b]...)
Affinity DataIC50:  1nMAssay Description:inhibition of (-)-[3H]-nicotine binding to torpedo electroplax membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Stauffer Chemical

Curated by ChEMBL
LigandPNGBDBM50023331((+)-pyrido[3,4-b]homotropane | (+/-)-pyrido[3,4-b]...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of [3H]-MCC binding to torpedo electroplax membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50023331((+)-pyrido[3,4-b]homotropane | (+/-)-pyrido[3,4-b]...)
Affinity DataKd:  1.06nMAssay Description:Dissociation constant for nicotinic acetylcholine receptor alpha 7 from human neuroblastoma SH-SY5Y cells; n=3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50023331((+)-pyrido[3,4-b]homotropane | (+/-)-pyrido[3,4-b]...)
Affinity DataEC50:  5.50E+3nMAssay Description:Intrinsic activity at human alpha-4-beta-2 nACHR in SH-EP1 cells relative to AChMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed