BDBM50031460 (2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E)-ylidene]-3,7-dimethyl-octa-2,4,6-trienoic acid::CHEMBL46398

SMILES CCC1=C(C(C)C)\C(CCC1)=C\C(\C)=C\C=C\C(\C)=C\C(O)=O

InChI Key InChIKey=OZUIXDDSOLQKNK-WXVUQSRRSA-N

Data  12 IC50  6 Kd  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50031460   

TargetRetinoic acid receptor RXR-alpha(Mus musculus)
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50031460((2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of binding to retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Mus musculus)
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50031460((2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...)
Affinity DataEC50:  2nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoid A receptor RAR gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Mus musculus)
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50031460((2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...)
Affinity DataEC50:  33nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoid A receptor RAR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Mus musculus)
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50031460((2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...)
Affinity DataIC50:  10nMAssay Description:Inhibition of binding to retinoid A receptor RAR gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Mus musculus)
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50031460((2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...)
Affinity DataIC50:  10nMAssay Description:Inhibition of binding to murine Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCellular retinoic acid-binding protein 2(Mus musculus)
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50031460((2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...)
Affinity DataKd:  1.40nMAssay Description:Binding affinity for mouse Cytoplasmic retinoic acid binding protein type 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50031460((2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...)
Affinity DataKd: >200nMAssay Description:Binding affinity for human Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCellular retinoic acid-binding protein 1(Mus musculus)
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50031460((2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...)
Affinity DataKd:  0.300nMAssay Description:Binding affinity for mouse Cytoplasmic retinoic acid binding protein type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Mus musculus)
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50031460((2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...)
Affinity DataIC50:  6nMAssay Description:Inhibition of murine Retinoic acid receptor RAR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCellular retinoic acid-binding protein 1(Gallus gallus)
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50031460((2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...)
Affinity DataIC50:  700nMAssay Description:Inhibition of binding to chick skin Cytoplasmic retinoic acid binding proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Mus musculus)
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50031460((2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...)
Affinity DataIC50:  11nMAssay Description:Inhibition of murine Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Mus musculus)
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50031460((2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of binding to murine Retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Mus musculus)
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50031460((2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of [3H]-ATRA binding to mouse Retinoic acid receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCellular retinoic acid-binding protein 1(Mus musculus)
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50031460((2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...)
Affinity DataKd:  0.300nMAssay Description:Inhibition of [3H]-ATRA binding to murine Cytoplasmic retinoic acid binding protein (CRABP) type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50031460((2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...)
Affinity DataKd: >200nMAssay Description:Inhibition of binding to human Retinoic acid receptor RXR DEF domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCellular retinoic acid-binding protein 2(Mus musculus)
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50031460((2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...)
Affinity DataKd:  1.40nMAssay Description:Inhibition of [3H]-ATRA binding to murine Cytoplasmic retinoic acid binding protein (CRABP) type 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Mus musculus)
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50031460((2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...)
Affinity DataIC50:  11nMAssay Description:Inhibition of [3H]-ATRA binding to mouse Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCellular retinoic acid-binding protein 1(Gallus gallus)
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50031460((2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...)
Affinity DataIC50:  700nMAssay Description:Inhibition of [3H]-ATRA binding to chick skin Cytoplasmic retinoic acid binding proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Mus musculus)
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50031460((2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...)
Affinity DataIC50:  6nMAssay Description:Inhibition of binding to retinoid A receptor RAR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Mus musculus)
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50031460((2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...)
Affinity DataIC50:  14nMAssay Description:Inhibition of binding to retinoid A receptor RAR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Mus musculus)
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50031460((2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...)
Affinity DataEC50: >2.00E+3nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoid X receptor RXR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Mus musculus)
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50031460((2E,4E,6E)-8-[3-Ethyl-2-isopropyl-cyclohex-2-en-(E...)
Affinity DataEC50:  20nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoid A receptor RAR betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed