BDBM50034147 (4aR,6aS,7S,11aR)-1,4a,6a-Trimethyl-2-oxo-hexadecahydro-indeno[5,4-f]quinoline-7-carboxylic acid diethylamide::CHEMBL279134

SMILES CCN(CC)C(=O)[C@H]1CCC2C3CC[C@H]4N(C)C(=O)CC[C@]4(C)C3CC[C@]12C

InChI Key InChIKey=GNWBLLYJQXKPIP-XCWVSVQESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50034147   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034147((4aR,6aS,7S,11aR)-1,4a,6a-Trimethyl-2-oxo-hexadeca...)
Affinity DataIC50:  7.5nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type 2 in SW-13-transfected cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Mus musculus)
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034147((4aR,6aS,7S,11aR)-1,4a,6a-Trimethyl-2-oxo-hexadeca...)
Affinity DataIC50:  463nMAssay Description:In vitro inhibition of DHT (dihydrotestosterone) on proliferation of androgen-sensitive cancer Schionogi (SC-3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Chul Research Center

Curated by ChEMBL
LigandPNGBDBM50034147((4aR,6aS,7S,11aR)-1,4a,6a-Trimethyl-2-oxo-hexadeca...)
Affinity DataIC50:  4.10nMAssay Description:In vitro inhibition of human steroid 5-alpha-reductase type I in Du-145 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed