BDBM50075312 (Difluoro-naphthalen-2-yl-methyl)-phosphonic acid::CHEMBL60857::difluoro(2-naphthyl)methylphosphonate::difluoro(naphthalen-2-yl)methylphosphonate
SMILES OP(O)(=O)C(F)(F)c1ccc2ccccc2c1
InChI Key InChIKey=XJGUKDJAOUXADK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50075312
Affinity DataKi: 1.79E+5nMAssay Description:Binding affinity of the compound towards recombinant human Protein-tyrosine phosphatase 1B was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 1.79E+5nMAssay Description:Inhibitory activity against Yersinia Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
Affinity DataKi: 1.97E+5nMAssay Description:Compound was evaluated for inhibitory constant against PTP1BMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human PTP1B expressed in Escherichia coli BL21(DE3) cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Compound was evaluated for 50% inhibition of CD45 using uM)More data for this Ligand-Target Pair
Affinity DataIC50: 9.50E+4nMAssay Description:Compound was evaluated for 50% inhibition of PTP1B using uM)More data for this Ligand-Target Pair
Affinity DataIC50: 7.18E+5nMAssay Description:Inhibitory potency of the compound for the protein tyrosine phosphatase(PTP 1B)-catalyzed hydrolysis of p-nitrophenol phosphateMore data for this Ligand-Target Pair