BDBM50084974 CHEMBL3427402
SMILES Cc1cc(OC(F)(F)F)ccc1-c1c(Oc2ccc(\C=C\C(O)=O)cc2)c2ccc(O)cc2oc1=O
InChI Key InChIKey=SGOPFRYXITYBBT-NYYWCZLTSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50084974
Affinity DataIC50: 0.5nMAssay Description:Binding affinity to ER alpha (unknown origin) by LanthaScreen TR-FRET competitive binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of hERG channel by electrophysiologyMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Agonist activity at ER alpha in human MCF7 cells assessed as PR gene expression after 24 hrs by laser scanning imaging cytometer analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Antagonist activity at ER alpha in human MCF7 cells assessed as inhibition of estradiol-induced PR expression treated for 24 hrs after incubation wit...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Suppression of ER alpha in human MCF7 cells after 24 hrs by immunostaining analysisMore data for this Ligand-Target Pair