BDBM50085536 3,4,5-Trihydroxybenzoate, X::3,4,5-trihydroxybenzoic acid::CHEMBL288114::Gallic Acid, F::gallic acid
SMILES OC(=O)c1cc(O)c(O)c(O)c1
InChI Key InChIKey=LNTHITQWFMADLM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 46 hits for monomerid = 50085536
Affinity DataKi: 2.25E+3nMAssay Description:Inhibition of human CA2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.20E+3nMAssay Description:Inhibition of human CA1 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.08E+3nMAssay Description:Inhibition of human CA5A by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.13E+3nMAssay Description:Inhibition of Dicentrarchus labrax CA using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.07E+3nMAssay Description:Inhibition of human CA7 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.13E+3nMAssay Description:Inhibition of human CA6 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.99E+3nMAssay Description:Inhibition of human CA9 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.03E+3nMAssay Description:Inhibition of human CA14 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.49E+3nMAssay Description:Inhibition of human CA3 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.78E+3nMAssay Description:Inhibition of human CA12 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.80E+3nMAssay Description:Inhibition of human CA4 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.86E+3nMAssay Description:Inhibition of mouse CA13 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 9.97E+3nMAssay Description:Inhibition of human CA5B by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.00E+4nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
Affinity DataKi: 7.58E+5nM ΔG°: -4.25kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
Affinity DataKi: 1.05E+6nM ΔG°: -4.06kcal/molepH: 7.4 T: 2°CAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion using s...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human E-selectin after 2 hrsMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
National Cheng Kung University
Curated by ChEMBL
National Cheng Kung University
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of iNOS-mediated NO production in LPS-induced mouse BV2 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of C-terminal hexahistidine-tagged rat recombinant squalene epoxidase without N-terminal putative membrane domain expressed in Escherichia...More data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University Of Toledo
Curated by ChEMBL
University Of Toledo
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of polymerization in wild type HIV-1 RT with poly rC/dG12-18 template primer and [3H]dGTPMore data for this Ligand-Target Pair
TargetAutoinducer 2-binding periplasmic protein LuxP(Vibrio harveyi)
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at LuxP receptor in Vibrio harveyi MM32 assessed as inhibition of autoinducer2-mediated quorum sensing after 3 to 4 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+3nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMpH: 7.5 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMpH: 7.5 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataIC50: >2.00E+5nMpH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
TargetCMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1(Homo sapiens (Human))
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataIC50: 1.90E+4nMpH: 7.3 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
Target4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6(Homo sapiens (Human))
Schering-Plough Research Institute
Schering-Plough Research Institute
Affinity DataIC50: 1.40E+4nMpH: 7.3 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMpH: 7.3 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMpH: 7.3 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology
Curated by ChEMBL
Muroran Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 1.70nMAssay Description:Inhibition of amyloid beta 1 to 42 aggregation (unknown origin) incubated for 24 hrs by ThT fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.70E+6nMAssay Description:Inhibition of ACE by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of porcine pancreatic lipase using micellar solution of triolein as substrate preincubated for 5 mins before substrate addition measured a...More data for this Ligand-Target Pair
Affinity DataIC50: 4.65E+3nMAssay Description:Inhibition of DPP4 (unknown origin) using Gly-Pro-AMC as substrate preincubated for 4 secs followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+9nMAssay Description:Inhibition of baker's yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of CMG2 (40 to 217) C175A and R40C double mutant (unknown origin) interaction to full length PA E733C mutant expressed in Escherichia coli...More data for this Ligand-Target Pair
TargetPolypeptide N-acetylgalactosaminyltransferase 2(Homo sapiens (Human))
Shanghai Jiao Tong University
Curated by ChEMBL
Shanghai Jiao Tong University
Curated by ChEMBL
Affinity DataKd: 924nMAssay Description:Binding affinity of human recombinant FLAG-tagged ppGalNAcT2 expressed in HEK293 cells assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
TargetPolypeptide N-acetylgalactosaminyltransferase 2(Homo sapiens (Human))
Shanghai Jiao Tong University
Curated by ChEMBL
Shanghai Jiao Tong University
Curated by ChEMBL
Affinity DataKoff: 1.45E+3s-1Assay Description:Binding affinity of human recombinant FLAG-tagged ppGalNAcT2 expressed in HEK293 cells assessed as association rate by SPR analysisMore data for this Ligand-Target Pair
TargetPolypeptide N-acetylgalactosaminyltransferase 2(Homo sapiens (Human))
Shanghai Jiao Tong University
Curated by ChEMBL
Shanghai Jiao Tong University
Curated by ChEMBL
Affinity DataKon: 0.00134M-1s-1Assay Description:Binding affinity of human recombinant FLAG-tagged ppGalNAcT2 expressed in HEK293 cells assessed as dissociation rate by SPR analysisMore data for this Ligand-Target Pair
TargetPolypeptide N-acetylgalactosaminyltransferase 2(Homo sapiens (Human))
Shanghai Jiao Tong University
Curated by ChEMBL
Shanghai Jiao Tong University
Curated by ChEMBL
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of catalytic activity of human recombinant FLAG-tagged ppGalNAcT2 expressed in HEK293T cells and using 5-FAM labelled-EA2 peptide as subst...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Institute Of Agricultural And Food Biotechnology
Curated by ChEMBL
Institute Of Agricultural And Food Biotechnology
Curated by ChEMBL
Affinity DataIC50: 7.10E+6nMAssay Description:Inhibition of chymotrypsin-like activity of purified human 20S proteasome assessed as decrease in AMC hydrolysis using Suc-Leu-Leu-Val-Tyr-AMC as sub...More data for this Ligand-Target Pair
Affinity DataIC50: 6.93E+4nMAssay Description:Antagonist activity at TLR2 in mouse RAW264.7 cells assessed as PAM3CSK4-induced NO production measured after 24 hrs by Griess assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.43E+3nMAssay Description:Inhibition of alpha-synuclein (unknown origin) aggregation incubated for 3 days by thioflavin T based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.99E+5nMAssay Description:Inhibition of non-enzymatic glycation in hemoglobin (unknown origin) by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology
Curated by ChEMBL
Muroran Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 3.20nMAssay Description:Inhibition of amyloid beta 1 to 42 aggregation (unknown origin) incubated for 24 hrs by inverted fluorescence microscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.76E+4nMAssay Description:Inhibition of human L-selectin after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of human P-selectin after 2 hrsMore data for this Ligand-Target Pair