BDBM50085557 CHEMBL407239::Oligoadenylate analogue

SMILES Cc1nc(N)c2ncn([C@@H]3O[C@H](COP(O)(=O)O[C@@H]4[C@H](O)[C@@H](COP(O)(=O)O[C@@H]5[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]5n5cnc6c(N)nc(C)nc56)O[C@H]4n4cnc5c(N)nc(C)nc45)[C@@H](O)[C@H]3O)c2n1

InChI Key InChIKey=JSUKVNCAMCVYCE-AAXGZXMCSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50085557   

Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085557(CHEMBL407239 | Oligoadenylate analogue)
Affinity DataIC50:  1.06E+3nMAssay Description:Compound was tested for its binding ability, by displacement of p(A2'p)3A3'[32p]p5'Cp from recombinant human ribonuclease LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085557(CHEMBL407239 | Oligoadenylate analogue)
Affinity DataEC50:  30nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of [32P]-pC11U2C7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-5A-dependent ribonuclease(Homo sapiens (Human))
Gifu University

Curated by ChEMBL
LigandPNGBDBM50085557(CHEMBL407239 | Oligoadenylate analogue)
Affinity DataEC50:  16nMAssay Description:Activation of purified recombinant human Ribonuclease L by the compound was measured as degradation of poly (U) 3'[32P]p5'C3'pMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed