BDBM50099195 (2S,5R)-3,3-Dimethyl-4,4,7-trioxo-6-((E)-4-oxo-pent-2-enyl)-4lambda*6*-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid::CHEMBL6301

SMILES CC(=O)CC=CC1[C@@H]2N([C@@H](C(O)=O)C(C)(C)S2(=O)=O)C1=O

InChI Key InChIKey=KKSAGQLHTXTMBB-CAWIPBJDSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50099195   

TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099195((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-6-((E)-4-oxo-pen...)
Affinity DataIC50:  8.40E+3nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099195((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-6-((E)-4-oxo-pen...)
Affinity DataIC50:  7.10E+4nMAssay Description:In vitro inhibitory concentration against CCRA enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099195((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-6-((E)-4-oxo-pen...)
Affinity DataIC50:  1.00E+5nMAssay Description:In vitro inhibitory concentration against AmpC enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed