BDBM50102571 3-(3,4-Dichloro-phenyl)-6-hydroxy-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL421167

SMILES COC(=O)C1C2C[C@H](O)C(CC1c1ccc(Cl)c(Cl)c1)N2C

InChI Key InChIKey=NXVJVSJZXNWIHP-LKKSUFESSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50102571   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102571(3-(3,4-Dichloro-phenyl)-6-hydroxy-8-methyl-8-aza-b...)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102571(3-(3,4-Dichloro-phenyl)-6-hydroxy-8-methyl-8-aza-b...)
Affinity DataIC50:  6.09nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102571(3-(3,4-Dichloro-phenyl)-6-hydroxy-8-methyl-8-aza-b...)
Affinity DataIC50:  1.45E+3nMAssay Description:Inhibition of [3H]citalopram binding to the serotonin transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50102571(3-(3,4-Dichloro-phenyl)-6-hydroxy-8-methyl-8-aza-b...)
Affinity DataIC50:  6.09nMAssay Description:Inhibition of [3H]WIN-35428 binding to Dopamine transporter in rhesus (Macaca mulatta) or cynomolgus monkey (Macaca fascicularis) caudate-putamenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed