BDBM50109879 CHEMBL155301::Non peptidic, 4::{3-[2-(2,3-Difluoro-phenoxymethyl)-3-methyl-benzofuran-4-yloxy]-propyl}-pyridin-3-ylmethyl-amine

SMILES Cc1c(COc2cccc(F)c2F)oc2cccc(OCCCNCc3cccnc3)c12

InChI Key InChIKey=TTWYRLBZSORCIS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50109879   

TargetGlycylpeptide N-tetradecanoyltransferase(Candida albicans (Yeast))
Nippon Roche Research Center

LigandPNGBDBM50109879(CHEMBL155301 | Non peptidic, 4 | {3-[2-(2,3-Difluo...)
Affinity DataIC50:  4nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1(Homo sapiens (Human))
Nippon Roche Research Center

LigandPNGBDBM50109879(CHEMBL155301 | Non peptidic, 4 | {3-[2-(2,3-Difluo...)
Affinity DataIC50:  62nMAssay Description:Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50109879(CHEMBL155301 | Non peptidic, 4 | {3-[2-(2,3-Difluo...)
Affinity DataIC50:  3.70nMAssay Description:Inhibitory activity against Candida albicans (Nmt) assessed as inhibitory concentration (nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50109879(CHEMBL155301 | Non peptidic, 4 | {3-[2-(2,3-Difluo...)
Affinity DataIC50:  3.70nMAssay Description:Inhibitory activity against Candida albicans N-Myristoyltransferase (CaNmt) assessed as inhibitory concentration using substrate peptide and myristot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50109879(CHEMBL155301 | Non peptidic, 4 | {3-[2-(2,3-Difluo...)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibitory activity against human N-Myristoyltransferase (HsNmt) assessed as inhibitory concentration using substrate peptide and myristotyl-CoA at 0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed