BDBM50109882 3-(3-methyl-2-((2,3,4-trifluorophenoxy)methyl)benzofuran-4-yloxy)-N-(pyridin-3-ylmethyl)propan-1-amine::CHEMBL347048::{3-[3-Methyl-2-(2,3,4-trifluoro-phenoxymethyl)-benzofuran-4-yloxy]-propyl}-pyridin-3-ylmethyl-amine

SMILES Cc1c(COc2ccc(F)c(F)c2F)oc2cccc(OCCCNCc3cccnc3)c12

InChI Key InChIKey=FKIAZUIISXQFHC-UHFFFAOYSA-N

Data  7 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50109882   

TargetGlycylpeptide N-tetradecanoyltransferase(Candida albicans (Yeast))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50109882(3-(3-methyl-2-((2,3,4-trifluorophenoxy)methyl)benz...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of Candida albicans N-myristoyltransferseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Candida albicans (Yeast))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50109882(3-(3-methyl-2-((2,3,4-trifluorophenoxy)methyl)benz...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of Candida albicans N-myristoyltransferseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50109882(3-(3-methyl-2-((2,3,4-trifluorophenoxy)methyl)benz...)
Affinity DataIC50:  5.70nMAssay Description:Inhibitory activity against Candida albicans N-Myristoyltransferase (CaNmt) assessed as inhibitory concentration using substrate peptide and myristot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Candida albicans (Yeast))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50109882(3-(3-methyl-2-((2,3,4-trifluorophenoxy)methyl)benz...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of Candida albicans ATCC 90028 NMT using GLTISKLFRR-NH2 as substrate assessed as reduction in [3H]-myristoylated peptide reaction product ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50109882(3-(3-methyl-2-((2,3,4-trifluorophenoxy)methyl)benz...)
Affinity DataIC50: >4.30E+5nMAssay Description:Inhibitory activity against human N-Myristoyltransferase (HsNmt) assessed as inhibitory concentration using substrate peptide and myristotyl-CoA at 0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50109882(3-(3-methyl-2-((2,3,4-trifluorophenoxy)methyl)benz...)
Affinity DataIC50:  5.60nMAssay Description:Inhibitory activity against Candida albicans Nmt (CaNmt)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Homo sapiens (Human))
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50109882(3-(3-methyl-2-((2,3,4-trifluorophenoxy)methyl)benz...)
Affinity DataIC50:  3.70nMAssay Description:Inhibitory activity against Candida albicans (Nmt) assessed as inhibitory concentration (nM); 3.7-9.4 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed