BDBM50112356 CHEMBL3609373

SMILES OS(=O)(=O)C(C(=O)Nc1ccc(NC(=O)C(=O)Nc2ccc(I)cc2)cc1)c1ccccc1

InChI Key InChIKey=WYXKKFORWNIOFC-UHFFFAOYSA-N

Data  1 KI  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50112356   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataKi:  510nMAssay Description:Competitive inhibition of phosphatase activity of SHP2 (unknown origin) using pNPP as a substrate Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human LMWPTP using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase CDC14A(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human CDC14A using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human VHR using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human LAR using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase mu(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human PTPmu using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase gamma(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human PTPgamma using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of phosphatase activity of SHP2 (unknown origin) using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human PTPbeta using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human PTPalpha using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human Meg2 using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human HePTP using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human LYP using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of phosphatase activity of human PTP1B using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of phosphatase activity of human SHP1 using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase 5(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human PP5 using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase epsilon(Homo sapiens (Human))
Indiana University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50112356(CHEMBL3609373)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of phosphatase activity of human PTPepsilon using pNPP as a substrate after 10 mins by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed