BDBM50128172 4-(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3,3,3-trifluoro-2-hydroxypropyl)amino)phenoxy)phenol::4-{3-[[3-(1,1,2,2-Tetrafluoro-ethoxy)-benzyl]-(3,3,3-trifluoro-2-hydroxy-propyl)-amino]-phenoxy}-phenol::CHEMBL305400

SMILES OC(CN(Cc1cccc(OC(F)(F)C(F)F)c1)c1cccc(Oc2ccc(O)cc2)c1)C(F)(F)F

InChI Key InChIKey=YDDYUGZBVAFWEG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50128172   

TargetCholesteryl ester transfer protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128172BDBM50128172(4-{3-[[3-(1,1,2,2-Tetrafluoro-ethoxy)-benzyl]-(3,3...)
Affinity DataIC50: 3.50E+3nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128172BDBM50128172(4-{3-[[3-(1,1,2,2-Tetrafluoro-ethoxy)-benzyl]-(3,3...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of CETPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Rabbit)
Al-Zaytoonah Private University of Jordan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128172BDBM50128172(4-{3-[[3-(1,1,2,2-Tetrafluoro-ethoxy)-benzyl]-(3,3...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of CETP in rabbit serum after 1 hr by fluorescent cholesteryl esters transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed