BDBM50136755 CHEMBL3752386
SMILES COc1ccc(cc1)C1(CNC(=O)c2ccc(NC(=O)c3ccco3)cc2Cl)CCOCC1
InChI Key InChIKey=PFKDFLVWKSDYJO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50136755
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ARTD1 by fluorescence analysisMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Homo sapiens (Human))
University Of Oulu
Curated by ChEMBL
University Of Oulu
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of tankyrase in WNT3a-stimulated human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Oulu
Curated by ChEMBL
University Of Oulu
Curated by ChEMBL
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of human TNKS2 by fluorescence analysisMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
University Of Oulu
Curated by ChEMBL
University Of Oulu
Curated by ChEMBL
Affinity DataIC50: 562nMAssay Description:Inhibition of human TNKS1 by fluorescence analysisMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Oulu
Curated by ChEMBL
University Of Oulu
Curated by ChEMBL
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of human TNKS2 by fluorescence analysisMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
University Of Oulu
Curated by ChEMBL
University Of Oulu
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Inhibition of human TNKS1 by fluorescence analysisMore data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP12(Homo sapiens (Human))
University Of Oulu
Curated by ChEMBL
University Of Oulu
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ARTD12 by fluorescence analysisMore data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Homo sapiens (Human))
University Of Oulu
Curated by ChEMBL
University Of Oulu
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ARTD3 by fluorescence analysisMore data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP4(Homo sapiens (Human))
University Of Oulu
Curated by ChEMBL
University Of Oulu
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ARTD4 by fluorescence analysisMore data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP15(Homo sapiens (Human))
University Of Oulu
Curated by ChEMBL
University Of Oulu
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ARTD7 by fluorescence analysisMore data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Oulu
Curated by ChEMBL
University Of Oulu
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ARTD8 by fluorescence analysisMore data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
University Of Oulu
Curated by ChEMBL
University Of Oulu
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ARTD10 by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ARTD2 by fluorescence analysisMore data for this Ligand-Target Pair