BDBM50141611 CHEMBL3758739
SMILES CC1(C)OCc2c1nc(nc2Nc1n[nH]c2c(Cl)cccc12)-c1cn[nH]c1C(F)F
InChI Key InChIKey=SIMOEFIOKHUVBO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50141611
Affinity DataKi: 1.70nMAssay Description:Inhibition of EGFR deletion (746 to 750 residues) mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of EGFR T790M/deletion (746 to 750 residues) mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of EGFR T790M/L858R mutant autophosphorylation in human H1975 cellsMore data for this Ligand-Target Pair