BDBM50159994 CHEMBL3786996::US10844032, Example 170
SMILES Cc1cc(OCCCc2c([nH]c3ccccc23)C(=O)NS(=O)(=O)CCNC(=O)c2cccn2C)cc(C)c1Cl
InChI Key InChIKey=UIHPPEAWUFEMKF-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50159994
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Displacement of FITC-Bak-BH3 peptide probe from N-terminal His-tagged human Mcl-1 (172 to 327 residues) expressed in Escherichia coli BL21(DE3) after...More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [172-327](Homo sapiens (Human))
Vanderbilt University
US Patent
Vanderbilt University
US Patent
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair