BDBM50162136 CHEMBL3792924

SMILES Cn1c(cc(OCc2cc(F)c(Oc3ccc(Cl)c(c3)C(F)(F)F)c(F)c2)nc1=O)N1CCS(=O)(=O)CC1

InChI Key InChIKey=FLCSHCSBIFPQJJ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50162136   

TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50162136(CHEMBL3792924)
Affinity DataKd:  185nMAssay Description:Binding affinity to human Lp-PLA2 by ITC assayMore data for this Ligand-Target Pair
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50162136(CHEMBL3792924)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of recombinant human Lp-PLA2 using 2-thio-PAF as substrate measured for 10 mins by plate reader analysisMore data for this Ligand-Target Pair