BDBM50166601 CHEMBL3798679

SMILES CC1(C)NC(=O)c2ccc(cc2N1Cc1ccccc1)-n1c2cccnc2[nH]c1=O

InChI Key InChIKey=LOPPJVYTMBRTCK-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50166601   

TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50166601(CHEMBL3798679)
Affinity DataIC50:  0.460nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus preincubated for 5 mins using fluorescein-PKC substrate measu...More data for this Ligand-Target Pair
TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50166601(CHEMBL3798679)
Affinity DataIC50:  16nMAssay Description:Inhibition of PKCtheta in human Jurkat cells after overnight incubation by luminescence analysisMore data for this Ligand-Target Pair