BDBM50178330 (3S,10S,13S,17S,E)-13-methyl-10-(prop-1-enyl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol::CHEMBL202415

SMILES C\C=C\[C@]12CC[C@H](O)CC1=CCC1C3CC[C@H](O)[C@@]3(C)CCC21

InChI Key InChIKey=IPSPNXNCRNDAPA-QYLAZLGHSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50178330   

TargetAndrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178330((3S,10S,13S,17S,E)-13-methyl-10-(prop-1-enyl)-2,3,...)
Affinity DataIC50:  843nMAssay Description:Inhibitory activity against ARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178330((3S,10S,13S,17S,E)-13-methyl-10-(prop-1-enyl)-2,3,...)
Affinity DataIC50:  96nMAssay Description:Binding affinity to human ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178330((3S,10S,13S,17S,E)-13-methyl-10-(prop-1-enyl)-2,3,...)
Affinity DataEC50:  47nMAssay Description:Effect on transactivation of ALP gene expression in HEK293 cells transfected with hERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178330((3S,10S,13S,17S,E)-13-methyl-10-(prop-1-enyl)-2,3,...)
Affinity DataIC50:  1.16E+3nMAssay Description:Binding affinity to human ERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178330((3S,10S,13S,17S,E)-13-methyl-10-(prop-1-enyl)-2,3,...)
Affinity DataEC50:  39nMAssay Description:Effect on transactivation of ALP gene expression in HEK293 cells transfected with hERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed